X-linked myotubular myopathy (XLMTM) is a severe monogenetic disorder of the skeletal muscle.It is caused by loss-of-expression/function goldwell topchic 7n@bp mutations in the myotubularin (MTM1) gene.Much of what is known about the disease, as well as the treatment strategies, has been uncovered through experimentation in pre-clinical models, par
Saeid Maghsoudi,1 Bahareh Taghavi Shahraki,1 Navid Rabiee,2 Yousef Fatahi,3– 5 Rassoul Dinarvand,3,4 Maryam Tavakolizadeh,6 Sepideh Ahmadi,7,8 Mohammad Rabiee,9 Mojtaba Bagherzadeh,2 Ali Pourjavadi,6 Hassan Farhadnejad,10 Mohammadreza Tahriri,11 Thomas J Webster,12 Lobat Tayebi11 1Department of Medicinal Chemistry, Shiraz University of Techno
AbstractAim: Tuberculous meningitis is an infectious disease of isidor oreiller the central nervous system caused by Mycobacterium tuberculosis (M.tuberculosis).It mainly involves the meninges and brain parenchyma, as well as the spinal cord and meninges; Disability and mortality rates are high.In recent years, due to the increase of drug-resistant